Journal of Craniomaxillofacial Reserarch

• Ahmad Jafari

Department of Community Oral Health, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

• Abbas Karimi

Department of Oral and Maxillofacial Surgery, School of Dentistry, Craniomaxillofacial Research Center, Tehran University of Medical Sciences, Tehran, Iran.

• Mitra Salamat

Dentist, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

KEYWORDS: Oral cancer, Squamous cell carcinoma, Oral squamous cell carcinoma.

ABSTRACT

 Background: Squamous cell carcinoma (SCC) is the most common head and neck cancer. According to the role of epidemiological data in planning and effective interventions, the aim for the current study was a five-year review of oral squamous cell carcinoma. Materials and Methods: In this cross-sectional study, the data was derived from 76 recorded files of patients with oral SCC (OSCC) in Shariati hospital at the Tehran University of Medical Sciences from 2010 to 2015. The data included demographic variables, risk factors and lesion characteristics. The collected data has been analyzed by SPSS software and descriptive analysis was presented. Results: In this study 52 patients were male (68.4%) and 24 patients were female (31.6%). The mean age of patients was 60.5 ± 12.80 years. The prevalence of OSCC among men was 2.2 times more than women. The most common sites of tumor were buccal mucosa (36.8%) and then mandibular ridge (34.2%) and the most common clinical symptoms of tumor were painful tooth/teeth which are not mobile (69.7%) and ulcer (64.5%). Based on histological grading, 64.5% of patients had well-differentiated lesions. Conclusion: The results of this study indicate that OSCC was more common in men and seniors. It also has involved buccal mucosa and mandibular ridge. The majorities of OSCC lesions were well-differentiated in the oral cavity, and were in stages two and three in TNM system. Keywords: Oral cancer, Squamous cell carcinoma, Oral squamous cell carcinoma.

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